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tecovirimat will enhance the stage or result of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Use Warning/Watch. Tecovirimat is a weak inhibitor of CYP2C8 and CYP2C19. Keep track of for adverse effects if coadministered with sensitive substrates of those enzymes.diazepam will increase levels of lomitapide by influencing hepatic/intestina